The most well known causes of secondary-lymphedema are radiation treatment for specific types of cancer such as testicular and breast cancers in women, or surgery. Additional causes of lymphedema include surgical procedures such as liposuction, surgery on blood vessels in limbs, other surgical procedures, as well as burns.
Globally, lymphedema is frequently caused by a parasite infection or filariasis. However, in the United States, lymphedema frequently occurs in women after breast cancer surgery, especially after radiation treatments. It is estimated that globally, there are up to 250 million individuals suffering with lymphedema.
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